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Clinical-grade, ultra-sensitive NGS liquid biopsy
SafeSEQ technology is designed to deliver a clinical-grade, ultra-sensitive NGS liquid biopsy solution to identify gene mutations to inform therapy selection, monitor tumor response, and identify emerging resistance.
NGS is a trusted and robust method for detecting multiple biomarkers with a single workflow. However, not all NGS assays perform the same, and it can be challenging to find the best test to fit your clinical development program's needs. Broad "pan-cancer" approaches can cover hundreds of biomarkers, making them powerful for early discovery; however, they lack optimization for specific intended uses and negatively impact overall data quality. Ultimately, this can slow patient identification and enrollment.
Rapid Custom SafeSEQ is the more sensitive, targeted, and tailored alternative to ensure you have access to the right test with the performance to provide the right information at the right time.
Solve ctDNA Detection & Analysis Challenges with SafeSEQ
Rapid Custom SafeSEQ provides custom ctDNA detection capabilities designed to optimize biomarker performance, development, and accelerate clinical evaluations.
Accelerate your clinical study with our expert molecular design capabilities, focused on the most relevant therapeutic targets and emerging resistance mutations
Maximize ctDNA analysis with limits of detection (LoD) 0.03-0.06%, an order of magnitude more sensitive than pan-cancer plasma NGS panels
Elevate data quality and streamline testing, providing deeper insights into therapeutic response, emerging resistance, and minimal/measurable residual disease (MRD)
Advance through clinical development with full diagnostic support, from IND through NDA, leveraging our proprietary platform
Sequencing power can be spread broadly across many genomic regions or focused on defined, clinically relevant regions. While a pan-cancer assay's breadth is tremendously powerful for biomarker discovery, SafeSEQ focuses exclusively on clinically relevant targets to achieve best-in-class LoD.
Advancing clinical oncology programs also demands flexibility. Rapid Custom SafeSEQ keeps pace with an ever-changing biomarker landscape by ensuring test performance is optimized, even when panels change.
By maintaining the right balance of coverage and sensitivity, SafeSEQ maximizes and expedites patient enrollment and delivers more in-depth insights into biomarker validity.